Programmed DNA assemblies serve as scaffolds for dye molecules with light-harvesting and photonic properties. Förster resonance energy transfer (FRET) theory predicts efficiency and temporal dynamics of energy transfer between dye molecules. We have developed a software that computes FRET properties of dye molecules attached to DNA nanostructures. The script with the documentation is available here. Note that users may need to apply the accessible volume algorithm to compute all possible positions of a dye attached to DNA through a flexible linker.

Users of this tool are kindly requested to cite the following reference:

  • Pan, K., Boulais, E., Yang, L., Bathe, M. Structure-based model for light-harvesting properties of nucleic acid nanostructures. Nucleic Acids Research, 42: 2159–2170 (2014). [ PubMed Article ]